Phenoxyethanol
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| Names | |
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| Preferred IUPAC name
2-Phenoxyethan-1-ol
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| Other names
Phenoxyethanol
Ethylene glycol monophenyl ether Phenoxytolarosol Dowanol EP / EPH Protectol PE Emery 6705 Rose ether 1-Hydroxy-2-phenoxyethane β-hydroxyethyl phenyl ether Phenyl cellosolve |
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| Identifiers | |
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3D model (JSmol)
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| ChEBI | |
| ChEMBL | |
| ChemSpider | |
| ECHA InfoCard | 100.004.173 |
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PubChem CID
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| UNII | |
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CompTox Dashboard (EPA)
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| Properties | |
| C8H10O2 | |
| Molar mass | 138.166 g·mol−1 |
| Appearance | Colorless oily liquid |
| Odor | faint rose-like |
| Density | 1.102 g/cm3 |
| Melting point | −2 °C (28 °F; 271 K) |
| Boiling point | 247 °C (477 °F; 520 K) |
| 26 g/kg | |
| Solubility | Chloroform, Alkali, diethyl ether: soluble |
| Solubility in peanut oil | slightly |
| Solubility in olive oil | slightly |
| Solubility in acetone | miscible |
| Solubility in ethanol | miscible |
| Solubility in glycerol | miscible |
| Vapor pressure | 0.001 kPa (0.00015 psi) |
| Thermal conductivity | 0.169 W/(m⋅K) |
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Refractive index (nD)
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1.534 (20 °C) |
| Occupational safety and health (OHS/OSH): | |
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Main hazards
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Harmful if swallowed Causes serious eye irritation |
| GHS labelling: | |
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| Warning | |
| NFPA 704 (fire diamond) | |
| Flash point | 126 °C (259 °F; 399 K) |
| 430 °C (806 °F; 703 K) | |
| Lethal dose or concentration (LD, LC): | |
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LD50 (median dose)
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1850 mg/kg (rat, oral) |
| Related compounds | |
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Related compounds
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phenetole |
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Phenoxyethanol is the organic compound with the formula C6H5OC2H4OH. It is a colorless oily liquid. It can be classified as a glycol ether and a phenol ether. It is a common preservative in vaccine formulations.[4]
Use[edit]
Phenoxyethanol has germicidal and germistatic properties.[5] It is often used together with quaternary ammonium compounds.
Phenoxyethanol is used as a perfume fixative; an insect repellent; an antiseptic;[6] a solvent for cellulose acetate, dyes, inks, and resins; a preservative for pharmaceuticals, cosmetics and lubricants;[7] an anesthetic in fish aquaculture;[8][9] and in organic synthesis.
Phenoxyethanol is an alternative to formaldehyde-releasing preservatives.[10] In Japan and the European Union, its concentration in cosmetics is restricted to 1%.[11]
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